The Renaissance period produced influential artists, including Leonardo da Vinci, celebrated for masterpieces like the "Mona Lisa" and "The Last Supper," and Michelangelo, renowned for his awe-inspiring sculptural and architectural works, including the Pietà and the ceiling of the Sistine Chapel. Raphael's paintings, such as the "School of Athens," and Donatello's sculptures signified their contributions to the era. Their collective impact revitalized art, architecture, and science, reshaping the cultural landscape and leaving an indelible legacy on the world of art.